I am generally under the impression that if your dexterity and coordination in the hands and feet don't match, you're in for a struggle. Why, because if you punch a hard right, but throw a hard left kick, it means that your "power strikes" are in opposite leads and therefore you must always resort to switching stance in order to deliver a power shot. Maybe some fighters out there have overcame it, but I think generally this isn't the best way to fight, and could lead to years and years of incorrect training. What do you guys think?