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https://www.reuters.com/business/he...a-highly-infectious-marburg-virus-2022-07-07/
DAKAR, July 7 (Reuters) - Two people in Ghana who later died tested positive for Marburg virus, a highly infectious disease similar to Ebola, the World Health Organization (WHO) said on Thursday.
Tests conducted in Ghana came back positive, but those results must be confirmed by a laboratory in Senegal for the cases to be considered confirmed, the WHO said in a statement.
The two patients in the southern Ashanti region both had symptoms including diarrhoea, fever, nausea and vomiting, before dying in hospital, the statement said.
If the cases are confirmed, this would be only the second outbreak of Marburg in West Africa. The first ever case of the virus was detected last year in Guinea, with no further cases identified.
"Preparations for a possible outbreak response are being set up swiftly as further investigations are underway," the WHO said.
There have been a dozen major Marburg outbreaks since 1967, mostly in southern and eastern Africa. Fatality rates have varied from 24% to 88% in past outbreaks depending on the virus strain and case management, according to the WHO.
https://www.cdc.gov/vhf/marburg/symptoms/index.html
Signs and Symptoms
After an incubation period of 2-21 days, symptom onset is sudden and marked by fever, chills, headache, and myalgia. Around the fifth day after the onset of symptoms, a maculopapular rash, most prominent on the trunk (chest, back, stomach), may occur. Nausea, vomiting, chest pain, a sore throat, abdominal pain, and diarrhea may appear. Symptoms become increasingly severe and can include jaundice, inflammation of the pancreas, severe weight loss, delirium, shock, liver failure, massive hemorrhaging, and multi-organ dysfunction.
Clinical diagnosis of Marburg virus disease (MVD) can be difficult. Many of the signs and symptoms of MVD are similar to other infectious diseases (such as malaria or typhoid fever) or viral hemorrhagic fevers that may be endemic in the area (such as Lassa fever or Ebola). This is especially true if only a single case is involved.
The case-fatality rate for MVD is between 23-90%. For a complete listing of the case fatality rates for each outbreak, please see the History of Outbreaks Table.
https://www.cdc.gov/vhf/marburg/outbreaks/chronology.html
https://www.reuters.com/business/he...a-highly-infectious-marburg-virus-2022-07-07/
DAKAR, July 7 (Reuters) - Two people in Ghana who later died tested positive for Marburg virus, a highly infectious disease similar to Ebola, the World Health Organization (WHO) said on Thursday.
Tests conducted in Ghana came back positive, but those results must be confirmed by a laboratory in Senegal for the cases to be considered confirmed, the WHO said in a statement.
The two patients in the southern Ashanti region both had symptoms including diarrhoea, fever, nausea and vomiting, before dying in hospital, the statement said.
If the cases are confirmed, this would be only the second outbreak of Marburg in West Africa. The first ever case of the virus was detected last year in Guinea, with no further cases identified.
"Preparations for a possible outbreak response are being set up swiftly as further investigations are underway," the WHO said.
There have been a dozen major Marburg outbreaks since 1967, mostly in southern and eastern Africa. Fatality rates have varied from 24% to 88% in past outbreaks depending on the virus strain and case management, according to the WHO.
https://www.cdc.gov/vhf/marburg/symptoms/index.html
Signs and Symptoms
After an incubation period of 2-21 days, symptom onset is sudden and marked by fever, chills, headache, and myalgia. Around the fifth day after the onset of symptoms, a maculopapular rash, most prominent on the trunk (chest, back, stomach), may occur. Nausea, vomiting, chest pain, a sore throat, abdominal pain, and diarrhea may appear. Symptoms become increasingly severe and can include jaundice, inflammation of the pancreas, severe weight loss, delirium, shock, liver failure, massive hemorrhaging, and multi-organ dysfunction.
Clinical diagnosis of Marburg virus disease (MVD) can be difficult. Many of the signs and symptoms of MVD are similar to other infectious diseases (such as malaria or typhoid fever) or viral hemorrhagic fevers that may be endemic in the area (such as Lassa fever or Ebola). This is especially true if only a single case is involved.
The case-fatality rate for MVD is between 23-90%. For a complete listing of the case fatality rates for each outbreak, please see the History of Outbreaks Table.
https://www.cdc.gov/vhf/marburg/outbreaks/chronology.html
